Malaria Genome Project

A detailed Summary of Malaria Genome Project

"The Malaria genome project, brings new hope"

Malaria is one of the world's most serious infectious diseases.

According to the World Health Organization, it kills 2.5 million people and infects 500 million each year worldwide. Malaria occurs in 100 countries, placing 40% of the world's population at risk. About 90% of cases are in tropical regions of Africa. About 95% of deaths are Africans under the age 5.

The most common form of malaria is the product of a nefarious partnership between the Anopheles Gambia mosquito and the Plasmodium Falciparum parasite. Mosquitoes pick up the parasite by feeding on an infected human host. The parasite lives in the mosquito's gut until the mosquito bites another human.

Malaria is currently reoccurring in many countries where it had been under control for decades. Anti-malarial drugs have lost much of their effectiveness. Plasmodium has evolved resistance to several drugs in many areas,

randomly broken, and each segment was inserted in to bacteria and cloned. The segments were analyzed to tease out the patterns of DNA's four chemical bases. The teams then used computers to sort through the information from the segments and put the genetic Humpty Dumpy back together again in a virtual form. The reassembled sequences were then checked for accuracy, yielding a final draft of the parasite genome that is 98 percent complete.

Currently, researchers need consistent, long-term funding to cover all aspects of malaria research, from genetics to mosquito control measures to social behavior studies, because the project is terribly under-funded. They have an annual budget of US $200 million, instead of the actual need that is about $2 billion.

vaccine. But right now, scientists say that they are still a long way from zapping the mosquito scourge.

These scientists report they have sequenced the genomes of both the parasite respon

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Approximate Word count = 640
Approximate Pages = 3 (250 words per page double spaced)

Category: Science

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