- a condition where a person has an experience of alternating periods of depressed moods and periods of manic or excited moods
- No one knows what exactly causes bipolar disorder. A study in the American Journal of Psychiatry reports "the extra signal-sending cells may lead to a kind of overstimulation, which makes sense considering the symptoms of bipolar disorder." Researchers have known for decades that a link exists between neurotransmitters and mood disorders, because drugs which alter these transmitters also relieve mood disorders. Some studies hypothesize that a low or high level of a specific neurotransmitter such as serotonin, norepinephrine or dopamine is the cause. Others indicate that an imbalance of these substances is the problem - i.e., that a specific level of a neurotransmitter is not as important as its amount in relation to the other neurotransmitters. Still other studies have found evidence that a change in the sensitivity of the receptors on nerve cells may be the issue.
- A factor involved is stress. A "stressful life event" can range from a death in the family to the loss of a job, from the birth of a child to a move. It can be pretty much anything, but it cannot be prec
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