Wear debris from devices used in total hip replacements can cause a condition called aseptic loosening. Aseptic loosening is a loosening of the total joint that is not caused by bacteria.4 It is attributed to wear particles of the implant, tissue response dominated by macrophages and degrading enzymes.2 In a loose total joint, the joint lies in a cavity

Orthopedic researchers are hard at work developing strategies to eliminate the problem of aseptic loosening. Studies into identification of genes that cause musculoskeletal deformities, proteomics, and cloning have advanced remarkably. Orthopedic surgeons look forward to the use of 'gene chips' that would allow them to review genetic analysis and select therapies tailored to the patient's biological makeup. New materials such as titanium and titanium alloys have helped. Advances in nanotechnology allows for the structure and function of body tissues to be created and mimicked in laboratories. Thanks to these advances, it is predicted that in the near future, use of plastics and metals will be replaced with use of cell-based materials. With the increased knowledge of factors controlling bone development and cell differentiation, composite materials will be fashioned that facilitate in-growth.1

that forms around it that is padded with loose

Some common words found in the essay are:
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Approximate Word count = 642
Approximate Pages = 3 (250 words per page double spaced)