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Genetic Cloning

Genetic scientists have been busy creating all kinds of solutions to some of the problems that the human and agricultural populations have been experiencing. One of the most promising has been in the area of transplantation. That is how Dolly the sheep, came about. Scientists have been trying to find a way to genetically engineer animals so that they can produce organs for humans that will not be rejected. Insulin from pigs has helped diabetics, pig valves can be used in cardiac repair, and pig skin helps burn victims,why not organs next ?

Pig 23 was genetically altered to incorporate human genes, in hopes of preventing rejection after transplantation. Pigs have organs that are about the right size and are similiar to humans, also the availability of these organs is great due to the reproductive cycle of pigs. The biggest obstacle is the issue of rejection. The new organ is typically killed, even before the surgeon closes the incision, due to hyperacute rejection. This process clots the blood, by forming antibodies that attach to the endothelium of the blood vessels in the organ. The complement system creates gaps in vessels, allowing gaps to form and clots to accumulate. Therefore, a complement inhibitor was developed as the ge


A final note is about butterflies. Monarch butterflies that were found to have eaten the pollen from genetically altered corn, a pest resistant variety, which killed or stunted the growth of the caterpillar. This is due to splicing Bacillus thuringiensis into the corn. Many say the pollen will not be blown far enough to affect the butterflies. Another possibility to be concerned about is that these genes can be picked up by wild species and transmitted in that plant.

Inserting genes has been accomplished to produce human lactoferrin in cows milk, from a founder cow named Herman, who sired a lot of females, carrying this gene. Lactoferrin is used in the intestines of immunocompromised patients to treat GI infections.

3. This agrobacterium is placed into a petri dish with plant cells, the agrobacterium latches onto one of the cells and and transfers the new gene into the cell's DNA.

Some agricultural products are being used to produce enzymes, antibodies, and other biopharmaceuticals. One company is using corn to poduce monoclonal antibodies, which is about 25-100 times cheaper than comparable products in mammalian cell culture. Some other things that are in production of an antibody to block herpes transmission and contraceptive anti-sperm antibody. It appears that there is news of a class of antibodies that can deliver drugs to diseased tissue linings, which will help cystic fibrosis patients. Another company is developing antibodies that can stimulate an immune reaction against cancer cells in patients with non- Hodgekins Lymphoma, in mice it has cured the cancer. There is also work on enzymes that will treat lipid metabolism disorders.

Many are excitited about the creation of the purple petunia. This transgenic product was created by putting a bacterial gene into a petunia- launching the age of agricultural biotechnology. The Agrobacterium tumefaciens typically injects it's DNA into the host, after the disease carrying genes had been removed, and then the newly spliced genes were introduced into the plant. This gene s

Some common words found in the essay are:
IX Pharming, Hodgekins Lymphoma, , Rh III, ATT Polly, genetically altered, cystic fibrosis, scientists trying, bacterial gene, carrying gene,
Approximate Word count = 1378
Approximate Pages = 6 (250 words per page double spaced)


  

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