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Hemophilia 2

In the human body, each cell contains 23 pairs of chromosomes, one of each pair inherited through the egg from the mother and the other from the sperm of the father. Of these chromosomes, those that determine sex are X and Y. Females have XX and males have XY. In addition to information concerning sex, the X chromosomes carry determinants for a number of other features of the body, including the levels of factor Vlll and lX. If the genetic information determining factors Vlll and lX is defective, hemophilia results. As a result, the protein factors needed for normal blood clotting are effected.

In males, the single X chromosome can not compensate for the lack, and will show the defect. In females however, only one of the two chromosomes will be abnormal. In very rare cases however, she will have inherited two defective X chromosomes and herself will be a hemophiliac. If she is not affected and the gene is recessive, she is now classified as a carrier. In some cases, there is no previous record of hemophilia in the family. Male children who would be born with hemophilia would be the result of the mutation of the gene.

There are two types of hemophilia: Hemophilia A and Hemophilia B. Hemophilia A, also known as "Cla


no matter what, so she will in the end be X XhX XY

because he has inherited either one of his

The concentrates previously mentioned are manufactured in large quantities and they are packaged in small bottles. The bottles can be stored in either the fridge or at room temperature for home therapy. The newest and most expensive concentrates are made from recombinant gene technology. The recombinant portion is manufactured from some human blood components, but also from other animal biological components.

ssical Hemophilia" is caused by a factor Vlll deficiency. This is the most common form of hemophilia. The second type of hemophilia, is Hemophilia B, and is sometimes referred to as the "Christmas Disease." Hemophilia B is caused by a factor lX deficiency. Both types of hemophilia are characterized by prolonged episodes of bleeding, especially into joints, muscles, internal organs, or even brain hemorrhaging.

Hemophilia is classified as severe, moderate, or mild, which indicates the expected frequency of bleeding. The normal clotting factor levels are on average 40% to 200%. If a hemophiliac has less than 2% clotting factors, then they are said to have severe hemophilia. If a person has severe hemophilia, factor Vlll of lX, depending on the type of hemophilia the hemophiliac suffers from, they will need the clotting factor Vlll or lX replaced several times a month, as a result of traumatic or apparently spontaneous bleeding. If a person suffers from moderate hemophilia, their clotting factors are 2% to 5%. Moder

Some common words found in the essay are:
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Approximate Word count = 1043
Approximate Pages = 4 (250 words per page double spaced)


  

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