ALS

A detailed Summary of ALS


Amyotrophic Lateral Sclerosis (ALS), also known as Motor Neuron Disease (MND), Mal Charcot, or Lou Gehrig's Disease, is a life threatening neurodegenerative disease. ALS causes the progressive loss of nervous system control of voluntary muscle systems by breaking down of motor neurons in the nerve cells in the brain and spinal core. It affects one in every 100,000 people, more men than woman, and symptoms don't usually develop until sufferers are in their fifties.

The symptoms of ALS include muscle weakness, decrease in muscle coordination and mass, loss of tissue due to a lack of nervous stimulation, possible paralysis, muscle cramps, voice impairment like hoarseness, slow or abnormal speech, difficulty swallowing and breathing, urinary urgency, leg ankle and feet swelling. Additionally, the nerves controlling muscles in wh


ALS is a terrible debilitating disease that we are only beginning to understand, and hopefully with new genetic technology we can find a cure.

ich use is lost, shrink and disappear.

Johns Hopkins researchers have previously shown that many ALS patients have little or no EAAT2 in certain areas of the brain and spinal cord, creating an excess of glutamate that kills the nerves that control muscles. If these mutations really are specific to ALS, then tests can be developed to detect them, which could help make the diagnosis to begin treatment much earlier and faster in the course of the disease.

This disease has a gradual onset that progressively worsens until death, which usually occurs within three to five years. There are three types of ALS. In some cases it is known that people inherit ALS, but often there are sporadic or non-inherited cases too. Th

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Approximate Word count = 582
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Category: Science

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