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A Virus

A virus is an ultramicroscopic infectious organism that, having no independent metabolic activity, can replicate only within a cell of another host organism. A virus consists of a core of nucleic acid, either RNA or DNA, surrounded by a coating of antigenic protein and sometimes a lipid layer surrounds it as well. The virus provides the genetic code for replication, and the host cell provides the necessary energy and raw materials. There are more than 200 viruses that are known to cause disease in humans. The Ebola virus, which dates back to 1976, has four strains each from a different geographic area, but all give their victims the same painful, often lethal symptoms.

The Ebola virus is a member of a family of RNA viruses' known as 'Filoviriade' and falling under one genus, 'Filovirus'. Marburg is a relative of the Ebola virus. The four strains of Ebola are Ebola Zaire, Ebola Sudan, Ebola Reston, and Ebola Tai. Each is named after the geographical location in which it was discovered. These filoviruses cause hemorrhagic fever, which is actually what kill victims of the Ebola virus. Hemorrhagic fever as defined in Mosby's Medical, Nursing, and Allied Health Dictionary as, a group of viral aerosol infections, characterized by


Ebola Reston was isolated in 1989 during an outbreak of cynomolgus monkeys in a quarantine in Reston, Virginia. These monkeys were imported to the U.S. from the Philippines. This was the only outbreak of the virus to go outside the continent of Africa. This Reston strain of Ebola appears to be highly pathogenic for some monkey species but not for man. No humans fell victim or even contracted the virus. This also is the only known strain to be able to be transferred through the air.

Ebola Zaire was identified in 1976 in Northern Zaire and was the first documented appearance of the virus. This strain of the virus effects humans and nonhuman primates. Close contact and dirty needles spread the Ebola virus. The center of the epidemic in Zaire involved a missionary hospital where they reused needles and syringes without sterilization. Most of the staff of the hospital got sick and died. This outbreak infected 318 with a death rate of 93%. Another fatal case was reported one year later in Zaire but nothing major ever became of it. The most recent case recorded was the infamous breakout in Kikwit, Zaire. This breakout had the world in an uproar about the possibility of this virus-spreading out globally. This outbreak appeared to have started with a patient who had surgery in Kikwit on April 10, 1995. Members of the surgical team then developed symptoms similar to those of a viral hemorrhagic fever disease. From there, the disease spread to more than 300 others. The most frequent symptoms at the onset were fever (94%), diarrhea (80%), and server weakness (74%); other symptoms included dysphagia (41%) and hiccups (15%). Clinical signs of bleeding occurred in 38% of cases. The World Heath Organization declared on August 24, 1995 that the outbreak of Ebola Zaire in Kikwit was officially over after killing 244 of its 315 known victims. This outbreak had a rate of death over 75%.

fever, chills, headache, malaise, and respiratory or GI symptoms, followed by capillary hemorrhages, and, in severe infection, oliguria, kidney failure, hypotension, and, possibly, death. The incubation period for Ebola Hemorrhagic Fever ranges from 2-21 days. The blood fails to clot and patients may bleed from injections sites and into the gastrointestinal tract, skin and internal organs. The Ebo

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Approximate Word count = 1542
Approximate Pages = 6 (250 words per page double spaced)


  

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