Human Genome Project
The Human Genome Project (HGP) is an international 13 year effort that began in October of 1990. The main objective of the project is to map the entire human DNA sequence. The project was planned to last 15 years, but rapid technological advances have moved the completion date to 2003. A rough draft of the human genome was completed in June 2000. Efforts are still underway to complete the finished high quality sequence. Many laboratories around the United States receive funding from either the Department of Energy (DOE) or the National Institutes of Health, or from both, for the HGP. Other researchers at colleges, universities, and laboratories throughout the United States also receive funding for the project. At any given time, the DOE Human Genome Project funds about 200 separate investigators. At least 18 countries have established human genome research programs. Some of the larger programs are in Australia, France, Sweden, China and the United Kingdom. Some developing countries are participating through studies of molecular biology techniques for genome research and studies of organisms that are particularly interesting to their geographic regions. The Human Genome Project Organization helps to
DNA forensics or DNA fingerprinting is another area that will be greatly affected by the completion of the project. Any type of organism can be identified by examination of DNA sequences unique to that species. Identifying individuals can be less precise at this time, although when DNA sequencing technologies progress further, direct characterization of very long DNA segments, and possibly even whole genomes, will become possible and will allow individual identification. To identify individuals, forensic scientists scan about 10 DNA regions that vary from person to person and use the data to create a DNA profile of the individual (sometimes called a DNA fingerprint). There is an extremely small chance that another person has the same DNA profile for a particular set of regions. There are many benefits that will come with DNA fingerprinting. Some include: identifying potential suspects whose DNA may match evidence left at crime scenes, exonerating people wrongly accused of cr! Understanding genomics will help us understand human evolution and the common biology we share with all of life. Comparative genomics between humans and other organisms such as mice already has led to similar genes associated with diseases and traits. Further comparative studies will help determine the yet unknown function of thousands of other genes. Comparing the DNA sequences of entire genomes of different microbes will provide new insights about relationships a
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