eral possible explanations have been bought forth. Most of these suggest that nicotine serves as a form of self-medication, either against the side effects of the antipsychotic medications or against other deficits associated with the illness. The nicotine in the cigarettes stimulates dopamine release and has mood elevating and anxiolytic effects in normal smokers. Smoking also seems to improve cognitive performance in normal smokers. . The nicotine increases the metabolism of some typical neuroleptics; smoking may reduce some side effects of antipsychotic medications by decreasing their levels in the blood. The participants that were used for one study were Vietnam era twins. The participants were interviewed using the diagnostic interview schedule, supplemented with additional inf

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