After leaving the Cagneys, Audie spent many nights sleeping in a gym owned by his friend, Terry Hunt. .

             His first starring role came in a 1949 released film by Allied Artists called, Bad Boy. In 1950 Murphy eventually got a contract with Universal-International (later called Universal) where he starred in 26 films, 23 of them westerns over the next 15 years. His 1949 autobiography To Hell and Back was a best seller. He dedicated this autobiographical book to PVT Lattie Tipton and to PVT Jose Sieja who was killed in action on the Anzio Beachhead in January, 1944. Murphy starred as himself in a film biography released by Universal-International in 1955 with the same title. The movie, To Hell and Back, held the record as Universal's highest grossing picture until 1975 when it was finally surpassed by the movie Jaws. In the mid-60s the studios switched from contract players to hiring actors on a picture-by-picture basis. Consequently, when his contract expired in 1965 Universal did not renew. This gave him the opportunity to work with other studios and independent film producers. In the 25 years that Audie spent in Hollywood, he made a total of 44 feature films. .

             Despite his success in Hollywood, Audie never forgot his rural Texas roots. He returned frequently to the Dallas area where he owned a small ranch for a while. He also had ranches in Perris, California and near Tucson, Arizona. He was a successful Thoroughbred and Quarter Horse racehorse owner and breeder, having interests in such great horses as "Depth Charge." His films earned him close to 3 million dollars in 23 years as an actor. Audie loved to gamble, and he bet on horses and different sporting events. He was also a great poker player. In his role as a prodigious gambler, he won and lost fortunes. .

             Audie Murphy wrote some poetry and was quite successful as a songwriter. Dozens of Audie Murphy's songs were recorded and released by such great performers as Dean Martin, Eddy Arnold, Charley Pride, Jimmy Bryant, Porter Waggoner, Jerry Wallace, Roy Clark, Harry Nilsson and many, many others.