1-7.3, rabbits have a pH of 8.2), and rabbits have a thinner cornea. Overall the Draize Test overestimates how irritating a product is to the human eye because rabbits eyes are more sensitive than the human eye (Freeberg). This test is also invalid because of the differences in the way the damage is evaluated. In a study performed by Carnegie University of Pittsburgh twelve substances were sent to twenty-four different laboratories. The results that came back for the same substances ranged from mild to severe reactions. Since the test itself is so unreliable companies should look into some alternatives. An alternative to using animals to test how harmful an ingredient is to the eye is a method called Eytex. Eytex uses a vegetable protein taken from jack beans. This clear protein gel turns clear when it comes in contact with irritating substances. This process is more accurate than the Draize Test is because the "damage" is measured by a spectrophotometer and not estimated by a person. The Eytex Test agrees well with the Draize Test, although the results should be compared to human eye irritation. Until better methods come along this test could be used instead of animals. Here are some comparisons of the Eytex Test to the Draize Test: % Agreement %Irritants Substances 85% 89% 101 80% 100% 465 The second column shows how closely related Eytex results agreed with Draize Test results, the third column shows what percentage of irritants were identified by Eytex, and the last column shows the number of substances were tested. There is also close agreement between laboratories on the results. One study showed 90% agreement between six different laboratories and ten substances (Kelly). Another study sent sixty substances to twelve different laboratories. In nine of thirteen categories of substances there was 100% agreement between the laboratories. There was 83%-93% agreement between the other four categories (Kelly).
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